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Snail + Slug (pSer246) antibody

The Rabbit Polyclonal anti- antibody has been validated for IHC (p). It is suitable to detect in samples from Human and Rat.
Catalog No. ABIN6989063

Quick Overview for Snail + Slug (pSer246) antibody (ABIN6989063)

Target

Snail + Slug

Reactivity

Human, Rat

Host

  • 18
Rabbit

Clonality

  • 18
Polyclonal

Conjugate

  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Un-conjugated

Application

  • 14
  • 3
  • 2
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

    pSer246

    Cross-Reactivity

    Human, Rat

    Predicted Reactivity

    Mouse,Cow,Sheep,Pig,Horse,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human phospho-SNAIL + SLUG (Ser246)

    Isotype

    IgG
  • Application Notes

    IHC-P 1:200-400

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Target

    Snail + Slug

    Background

    Synonyms: SNAIL + SLUG (phospho S246), p-SNAIL + SLUG (phospho S246), SNAIL + SLUG (phospho S246 + S251), SNAIL + SLUG (phospho Ser246 + Ser251), phospho-SNAIL(Ser246) + SLUG(Ser251), phospho-SNAIL(Ser246) + SLUG(Ser251), dJ710H13.1, MGC10182, Neural crest transcription factor Slug, Protein sna, Protein snail homolog 1, Protein snail homolog 2, Protein snail homolog, Slug homolog zinc finger protein, Slug zinc finger protein, SLUGH, SLUGH 1, SLUGH1, SLUGH2, SNA, Sna protein, SNAH, SNAI 2, snai1, SNAI1_HUMAN, Snai2, SNAI2_HUMAN, Snail 2, Snail homolog 1 (Drosophila), Snail homolog 2, Snail2, WS 2D, WS2D, Zinc finger protein SLUG, Zinc finger protein SNAI1, Zinc finger protein SNAI2.

    Background: Involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.

    Gene ID

    6615

    UniProt

    O95863
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